lgr4 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

lgr4

Leucine-rich repeat containing G protein-coupled receptor 4. (913 aa)

Predicted Functional Partners:

rspo1

0.995

LOC103478337

0.981

rspo2

0.963

LGR6

0.926

ENSPREP00000011770

0.907

znrf3

0.903

RSPO3

0.704

Fras1

0.693

rps27a

0.659

rln3

0.620

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000011770	LGR6	ENSPREP00000011770	ENSPREP00000029246	RING-type domain-containing protein.	Leucine rich repeat containing G protein-coupled receptor 6.	0.520
ENSPREP00000011770	LOC103478337	ENSPREP00000011770	ENSPREP00000019049	RING-type domain-containing protein.	R-spondin 3.	0.778
ENSPREP00000011770	lgr4	ENSPREP00000011770	ENSPREP00000033484	RING-type domain-containing protein.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.907
ENSPREP00000011770	rps27a	ENSPREP00000011770	ENSPREP00000018427	RING-type domain-containing protein.	Ribosomal protein S27a.	0.731
ENSPREP00000011770	rspo1	ENSPREP00000011770	ENSPREP00000008831	RING-type domain-containing protein.	R-spondin 1.	0.978
ENSPREP00000011770	rspo2	ENSPREP00000011770	ENSPREP00000022195	RING-type domain-containing protein.	R-spondin 2.	0.927
ENSPREP00000011770	znrf3	ENSPREP00000011770	ENSPREP00000006299	RING-type domain-containing protein.	Zinc and ring finger 3.	0.732
Fras1	lgr4	ENSPREP00000005000	ENSPREP00000033484	Uncharacterized protein.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.693
LGR6	ENSPREP00000011770	ENSPREP00000029246	ENSPREP00000011770	Leucine rich repeat containing G protein-coupled receptor 6.	RING-type domain-containing protein.	0.520
LGR6	LOC103478337	ENSPREP00000029246	ENSPREP00000019049	Leucine rich repeat containing G protein-coupled receptor 6.	R-spondin 3.	0.935
LGR6	lgr4	ENSPREP00000029246	ENSPREP00000033484	Leucine rich repeat containing G protein-coupled receptor 6.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.926
LGR6	rspo1	ENSPREP00000029246	ENSPREP00000008831	Leucine rich repeat containing G protein-coupled receptor 6.	R-spondin 1.	0.971
LGR6	rspo2	ENSPREP00000029246	ENSPREP00000022195	Leucine rich repeat containing G protein-coupled receptor 6.	R-spondin 2.	0.928
LGR6	znrf3	ENSPREP00000029246	ENSPREP00000006299	Leucine rich repeat containing G protein-coupled receptor 6.	Zinc and ring finger 3.	0.542
LOC103478337	ENSPREP00000011770	ENSPREP00000019049	ENSPREP00000011770	R-spondin 3.	RING-type domain-containing protein.	0.778
LOC103478337	LGR6	ENSPREP00000019049	ENSPREP00000029246	R-spondin 3.	Leucine rich repeat containing G protein-coupled receptor 6.	0.935
LOC103478337	lgr4	ENSPREP00000019049	ENSPREP00000033484	R-spondin 3.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.981
LOC103478337	rps27a	ENSPREP00000019049	ENSPREP00000018427	R-spondin 3.	Ribosomal protein S27a.	0.607
LOC103478337	rspo1	ENSPREP00000019049	ENSPREP00000008831	R-spondin 3.	R-spondin 1.	0.961
LOC103478337	rspo2	ENSPREP00000019049	ENSPREP00000022195	R-spondin 3.	R-spondin 2.	0.906