STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103462420Tight junction protein 1a; Belongs to the MAGUK family. (1693 aa)    
Predicted Functional Partners:
LOC103475799
F11 receptor, tandem duplicate 1.
   
 0.990
gja1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
 0.989
LOC103473229
Occludin a.
   
 0.980
tjp2
Tight junction protein 2a (zona occludens 2); Belongs to the MAGUK family.
    
0.968
jam3
Junctional adhesion molecule 3a.
    
 0.937
LOC103476216
Junctional adhesion molecule 3b.
    
 0.937
LOC103473228
MARVEL domain containing 2a.
   
 0.937
LOC103478155
Cingulin a.
   
 
 0.936
LOC103472710
Cingulin b.
   
 
 0.936
SRC
Tyrosine-protein kinase.
    
 0.931
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.