STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103459184DEF6 guanine nucleotide exchange factor c. (556 aa)    
Predicted Functional Partners:
met
MET proto-oncogene, receptor tyrosine kinase.
   
 0.648
LOC103464537
Macrophage stimulating 1 receptor a.
   
 0.648
mst1r
Macrophage stimulating 1 receptor b.
   
 0.648
LOC103463615
RAS protein activator like 3.
    
 0.494
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
    
 0.494
LOC103472458
Uncharacterized protein.
    
 0.494
LOC103460382
Uncharacterized protein.
    
 0.494
LOC103477581
Synaptic Ras GTPase activating protein 1b.
    
 0.494
LOC103479952
RAS protein activator like 2.
    
 0.494
dab2ip
DAB2 interacting protein b.
    
 0.494
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.