STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1Signal-induced proliferation-associated 1. (1042 aa)    
Predicted Functional Partners:
dysf
Dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive).
   
  
 0.685
LOC103480609
Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
      
 0.681
wdr27
Uncharacterized protein.
 
  
 
 0.529
smoc2
SPARC related modular calcium binding 2.
      
 0.525
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.525
RAP2A
RAP2A, member of RAS oncogene family.
    
 0.523
Rap2b
RAP2B, member of RAS oncogene family.
    
 0.523
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1.
   
 0.522
LOC103467749
Uncharacterized protein.
    
 0.497
rap1b
Uncharacterized protein.
    
 0.497
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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