zfhx3 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

zfhx3

Zinc finger homeobox 3. (3845 aa)

Predicted Functional Partners:

CSMD1

0.778

LOC103472465

0.681

LOC103475119

0.607

fancc

0.597

HDAC2

0.595

runx3

0.574

LOC103457845

0.572

LOC103477443

0.572

LOC103476608

0.548

med12

0.437

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSMD1	HDAC2	ENSPREP00000021200	ENSPREP00000030998	CUB and Sushi multiple domains 1.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.609
CSMD1	fancc	ENSPREP00000021200	ENSPREP00000025078	CUB and Sushi multiple domains 1.	FA complementation group C.	0.597
CSMD1	zfhx3	ENSPREP00000021200	ENSPREP00000034273	CUB and Sushi multiple domains 1.	Zinc finger homeobox 3.	0.778
HDAC2	CSMD1	ENSPREP00000030998	ENSPREP00000021200	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	CUB and Sushi multiple domains 1.	0.609
HDAC2	LOC103457845	ENSPREP00000030998	ENSPREP00000025064	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Runt-related transcription factor.	0.529
HDAC2	LOC103472465	ENSPREP00000030998	ENSPREP00000016914	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	CUB and Sushi multiple domains 3a.	0.493
HDAC2	LOC103476608	ENSPREP00000030998	ENSPREP00000006540	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Runt domain-containing protein.	0.483
HDAC2	LOC103477443	ENSPREP00000030998	ENSPREP00000027200	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Runt-related transcription factor.	0.529
HDAC2	fancc	ENSPREP00000030998	ENSPREP00000025078	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	FA complementation group C.	0.597
HDAC2	runx3	ENSPREP00000030998	ENSPREP00000004234	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Runt-related transcription factor.	0.529
HDAC2	zfhx3	ENSPREP00000030998	ENSPREP00000034273	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Zinc finger homeobox 3.	0.595
LOC103457845	HDAC2	ENSPREP00000025064	ENSPREP00000030998	Runt-related transcription factor.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.529
LOC103457845	LOC103475119	ENSPREP00000025064	ENSPREP00000027136	Runt-related transcription factor.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.727
LOC103457845	med12	ENSPREP00000025064	ENSPREP00000018993	Runt-related transcription factor.	Mediator complex subunit 12.	0.418
LOC103457845	zfhx3	ENSPREP00000025064	ENSPREP00000034273	Runt-related transcription factor.	Zinc finger homeobox 3.	0.572
LOC103472465	HDAC2	ENSPREP00000016914	ENSPREP00000030998	CUB and Sushi multiple domains 3a.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.493
LOC103472465	fancc	ENSPREP00000016914	ENSPREP00000025078	CUB and Sushi multiple domains 3a.	FA complementation group C.	0.646
LOC103472465	zfhx3	ENSPREP00000016914	ENSPREP00000034273	CUB and Sushi multiple domains 3a.	Zinc finger homeobox 3.	0.681
LOC103475119	LOC103457845	ENSPREP00000027136	ENSPREP00000025064	Transforming growth factor beta; Belongs to the TGF-beta family.	Runt-related transcription factor.	0.727
LOC103475119	LOC103476608	ENSPREP00000027136	ENSPREP00000006540	Transforming growth factor beta; Belongs to the TGF-beta family.	Runt domain-containing protein.	0.681