STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smad1Mothers against decapentaplegic homolog. (467 aa)    
Predicted Functional Partners:
SMAD4
Mothers against decapentaplegic homolog.
   
0.819
LOC103473773
Mothers against decapentaplegic homolog.
   
0.807
LOC103477474
Mothers against decapentaplegic homolog.
   
0.747
ski
V-ski avian sarcoma viral oncogene homolog a.
   
 0.708
ints1
Integrator complex subunit 1.
    
 0.707
ints5
Integrator complex subunit 5.
    
 0.704
bmp4
Bone morphogenetic protein 4.
    
 0.702
ints2
Integrator complex subunit 2.
   
 0.702
ints7
Integrator complex subunit 7.
   
 0.696
ints3
Integrator complex subunit 3.
    
 0.685
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.