STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hhipHedgehog interacting protein. (697 aa)    
Predicted Functional Partners:
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.984
LOC103461635
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.982
LOC103456683
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.982
dhh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.979
sorl1
Sortilin-related receptor, L(DLR class) A repeats containing.
    
 0.667
ptch1
Patched 1.
    
 
 0.639
ptch2
Patched 2.
    
 
 0.578
sufu
Suppressor of fused homolog.
      
 0.571
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.557
dym
Dymeclin.
      
 0.549
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.