STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mipepMitochondrial intermediate peptidase. (700 aa)    
Predicted Functional Partners:
nts
Neurotensin.
    
 0.797
fxn
Frataxin.
   
 
 0.680
xpnpep3
X-prolyl aminopeptidase 3, mitochondrial.
   
 
 0.672
pitrm1
Pitrilysin metallopeptidase 1.
    
 
 0.672
pmpca
Peptidase (mitochondrial processing) alpha.
   
  
 0.666
elac1
ElaC ribonuclease Z 1.
  
  
 0.663
dpp3
Dipeptidyl peptidase 3; Belongs to the peptidase M49 family.
   
  
 0.663
atp23
Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family.
      
 0.657
rplp0
Ribosomal protein, large, P0.
   
  
 0.652
sucla2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
  
 0.645
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
Server load: very high (>100%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.