STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrasMuscle RAS oncogene homolog. (208 aa)    
Predicted Functional Partners:
shoc2
SHOC2 leucine rich repeat scaffold protein.
    
 0.974
nf1
Neurofibromin 1b.
   
 0.967
LOC102235904
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.964
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.964
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
   
 0.958
sos1
Son of sevenless homolog 1 (Drosophila).
   
 0.946
sos2
Son of sevenless homolog 2 (Drosophila).
   
 0.946
rasgrp3
RAS guanyl releasing protein 3 (calcium and DAG-regulated).
    
 0.944
LOC102218567
RAS guanyl releasing protein 4.
    
 0.944
RASGRP1
RAS guanyl releasing protein 1.
    
 0.944
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.