STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP50Ubiquitin carboxyl-terminal hydrolase. (398 aa)    
Predicted Functional Partners:
pan2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...]
   
  
 0.640
mysm1
Myb-like, SWIRM and MPN domains 1.
   
 
 0.596
uspl1
Ubiquitin specific peptidase like 1.
   
 
 0.578
mrps9
Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.564
mrpl3
Mitochondrial ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.562
mrpl11
Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.
   
 
 0.562
Mrpl21
Mitochondrial ribosomal protein L21.
   
 
 0.550
rps2
Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
    
 
 0.549
mrps14
Mitochondrial ribosomal protein S14.
    
 
 0.541
yars1
Tyrosine--tRNA ligase.
      
 0.539
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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