STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102221568MYCN proto-oncogene, bHLH transcription factor. (464 aa)    
Predicted Functional Partners:
MAX
MYC associated factor X.
    
0.844
max
Myc associated factor X.
    
0.844
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.806
scap
SREBF chaperone.
   
 0.806
npc1
Niemann-Pick disease, type C1.
   
 0.806
kpnb1
Karyopherin (importin) beta 1.
    
 0.779
mbtps2
Membrane-bound transcription factor peptidase, site 2.
    
 0.737
aurka
Aurora kinase A; Belongs to the protein kinase superfamily.
    
 
 0.728
LOC102233914
Aurora kinase B; Belongs to the protein kinase superfamily.
    
 
 0.728
LOC102222224
Uncharacterized protein.
    
 
 0.663
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.