STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mmp15Matrix metallopeptidase 15b. (654 aa)    
Predicted Functional Partners:
LOC102223119
TIMP metallopeptidase inhibitor 2b.
   
 0.896
timp2
TIMP metallopeptidase inhibitor 2a.
   
 0.848
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 2.
    
 0.718
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.661
adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1.
      
 0.653
LOC102237346
Connexin 35.4.
      
 0.627
LOC102233196
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.627
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
    
 0.554
LOC102222459
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
    
 0.554
LOC102236177
Matrix metallopeptidase 13b.
  
0.515
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.