STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
cmpk1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (216 aa)    
Predicted Functional Partners:
cmpk2
Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial.
    
 0.971
umps
Uridine monophosphate synthetase.
   
 0.964
LOC102224167
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
 0.954
LOC102229193
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
 0.954
LOC102223567
Nucleoside diphosphate kinase.
  
 
 0.954
uprt
Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae).
  
 
 0.953
dut
Deoxyuridine triphosphatase.
  
 0.945
rrm2b
Ribonucleotide reductase M2 b.
   
 
 0.942
rrm2
Ribonucleotide reductase M2 polypeptide.
   
 
 0.942
LOC102238115
Uridine-cytidine kinase; Belongs to the uridine kinase family.
  
 
 0.940
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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