STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hs6st3Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (434 aa)    
Predicted Functional Partners:
LOC102238066
Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
  
  
 
0.901
LOC102222852
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.599
uggt2
UDP-glucose glycoprotein glucosyltransferase 2.
      
 0.560
tnfsf12
TNF superfamily member 12; Belongs to the tumor necrosis factor family.
      
 0.547
gpc5
Glypican 5a; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
  
  
 0.500
CLDN10
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.493
LOC102233887
Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.
      
 0.487
LOC102223888
Glypican 6b; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.487
gpc2
Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.487
LOC102234901
Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.487
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.