ro60 protein (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ro60

Ro60, Y RNA binding protein. (537 aa)

Predicted Functional Partners:

ssb

0.787

xpot

0.560

snrpc

0.560

hars1

0.506

cdt1

0.467

rnaseh2b

0.414

rtca

0.408

LOC102237555

0.408

exosc10

0.406

pop4

0.400

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102237555	ro60	ENSXMAP00000017666	ENSXMAP00000004847	FIP1 like 1b (S. cerevisiae).	Ro60, Y RNA binding protein.	0.408
cdt1	rnaseh2b	ENSXMAP00000038454	ENSXMAP00000025322	Chromatin licensing and DNA replication factor 1.	Ribonuclease H2, subunit B.	0.489
cdt1	ro60	ENSXMAP00000038454	ENSXMAP00000004847	Chromatin licensing and DNA replication factor 1.	Ro60, Y RNA binding protein.	0.467
exosc10	ro60	ENSXMAP00000011290	ENSXMAP00000004847	Exosome component 10.	Ro60, Y RNA binding protein.	0.406
exosc10	rtca	ENSXMAP00000011290	ENSXMAP00000005504	Exosome component 10.	RNA 3'-terminal phosphate cyclase.	0.891
hars1	ro60	ENSXMAP00000037900	ENSXMAP00000004847	Histidyl-tRNA synthetase.	Ro60, Y RNA binding protein.	0.506
pop4	ro60	ENSXMAP00000013893	ENSXMAP00000004847	POP4 homolog, ribonuclease P/MRP subunit.	Ro60, Y RNA binding protein.	0.400
rnaseh2b	cdt1	ENSXMAP00000025322	ENSXMAP00000038454	Ribonuclease H2, subunit B.	Chromatin licensing and DNA replication factor 1.	0.489
rnaseh2b	ro60	ENSXMAP00000025322	ENSXMAP00000004847	Ribonuclease H2, subunit B.	Ro60, Y RNA binding protein.	0.414
ro60	LOC102237555	ENSXMAP00000004847	ENSXMAP00000017666	Ro60, Y RNA binding protein.	FIP1 like 1b (S. cerevisiae).	0.408
ro60	cdt1	ENSXMAP00000004847	ENSXMAP00000038454	Ro60, Y RNA binding protein.	Chromatin licensing and DNA replication factor 1.	0.467
ro60	exosc10	ENSXMAP00000004847	ENSXMAP00000011290	Ro60, Y RNA binding protein.	Exosome component 10.	0.406
ro60	hars1	ENSXMAP00000004847	ENSXMAP00000037900	Ro60, Y RNA binding protein.	Histidyl-tRNA synthetase.	0.506
ro60	pop4	ENSXMAP00000004847	ENSXMAP00000013893	Ro60, Y RNA binding protein.	POP4 homolog, ribonuclease P/MRP subunit.	0.400
ro60	rnaseh2b	ENSXMAP00000004847	ENSXMAP00000025322	Ro60, Y RNA binding protein.	Ribonuclease H2, subunit B.	0.414
ro60	rtca	ENSXMAP00000004847	ENSXMAP00000005504	Ro60, Y RNA binding protein.	RNA 3'-terminal phosphate cyclase.	0.408
ro60	snrpc	ENSXMAP00000004847	ENSXMAP00000017975	Ro60, Y RNA binding protein.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.560
ro60	ssb	ENSXMAP00000004847	ENSXMAP00000004905	Ro60, Y RNA binding protein.	Small RNA binding exonuclease protection factor La.	0.787
ro60	xpot	ENSXMAP00000004847	ENSXMAP00000002856	Ro60, Y RNA binding protein.	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.	0.560
rtca	exosc10	ENSXMAP00000005504	ENSXMAP00000011290	RNA 3'-terminal phosphate cyclase.	Exosome component 10.	0.891