STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
get3ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (341 aa)    
Predicted Functional Partners:
LOC102229100
Guided entry of tail-anchored proteins factor 1.
    
 0.995
get4
Guided entry of tail-anchored proteins factor 4.
    
 0.994
camlg
Calcium modulating ligand.
    
 0.958
acp1
LMWPc domain-containing protein.
    
 0.951
oca2
Oculocutaneous albinism II.
    
 0.923
rad23a
RAD23 homolog A, nucleotide excision repair protein a.
   
 0.891
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 0.891
bag6
BCL2 associated athanogene 6.
    
 0.876
stx5
Syntaxin 5A; Belongs to the syntaxin family.
   
 0.860
LOC102235073
Ubiquitin like 4A.
    
 0.793
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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