STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
e2f7E2F transcription factor 7. (794 aa)    
Predicted Functional Partners:
tfdp1
Transcription factor.
    
 
 0.673
e2f8
E2F transcription factor 8.
  
  
0.620
e2f1
E2F transcription factor 1.
   
0.590
nfia
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
      
 0.560
foxm1
Forkhead box M1.
   
  
 0.554
nek2
NIMA-related kinase 2.
   
  
 0.522
ttk
Ttk protein kinase.
   
  
 0.504
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
  
 0.495
LOC102225329
Retinoblastoma-like 2 (p130).
   
 
 0.484
rbl1
Retinoblastoma-like 1 (p107).
   
 
 0.484
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.