STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcf11PCF11 cleavage and polyadenylation factor subunit. (1691 aa)    
Predicted Functional Partners:
clp1
Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]
    
 0.999
cstf3
Cleavage stimulation factor, 3' pre-RNA, subunit 3.
    
 0.997
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.995
sympk
Symplekin.
    
 0.990
cpsf1
Cleavage and polyadenylation specific factor 1.
    
 0.989
cstf2
Cleavage stimulation factor, 3' pre-RNA, subunit 2.
    
 0.988
LOC102237555
FIP1 like 1b (S. cerevisiae).
    
 0.974
LOC102220704
Cleavage and polyadenylation specific factor 3.
   
 0.970
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.970
papolg
Poly(A) polymerase gamma.
    
 0.941
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.