STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ncf4Neutrophil cytosolic factor 4. (350 aa)    
Predicted Functional Partners:
ncf1
Neutrophil cytosolic factor 1.
   
0.988
ncf2
Neutrophil cytosolic factor 2.
   
0.980
ENSXMAP00000027050
NADPH oxidase activator 1.
   
 0.972
LOC102219145
Cytochrome b-245, alpha polypeptide.
   
 0.899
nox4
FAD-binding FR-type domain-containing protein.
   
 0.746
LOC102232835
Cytochrome b-245, beta polypeptide (chronic granulomatous disease).
   
 0.710
duox1
Dual oxidase.
   
 0.687
nox1
NADPH oxidase 1.
   
 0.656
nox5
NADPH oxidase, EF-hand calcium binding domain 5.
   
 0.653
RAC1
Rac family small GTPase 1.
   
 0.639
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.