STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB1Phosphoinositide phospholipase C. (1050 aa)    
Predicted Functional Partners:
LOC102238377
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.622
LOC102230612
Uncharacterized protein.
    
 0.622
LOC102230875
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.622
LOC102218075
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.622
edn1
Endothelin 1.
     
 0.610
LOC102222422
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
    
 0.559
LOC102224032
Uncharacterized protein.
      
 0.547
cacna1a
Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b.
   
 
 0.533
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
  
  
0.514
LOC102222767
Uncharacterized protein.
    
 0.509
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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