node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC102237630 | dkc1 | ENSXMAP00000001647 | ENSXMAP00000023561 | TERF1 (TRF1)-interacting nuclear factor 2. | Dyskeratosis congenita 1, dyskerin. | 0.838 |
LOC102237630 | gar1 | ENSXMAP00000001647 | ENSXMAP00000002316 | TERF1 (TRF1)-interacting nuclear factor 2. | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. | 0.662 |
LOC102237630 | nhp2 | ENSXMAP00000001647 | ENSXMAP00000007046 | TERF1 (TRF1)-interacting nuclear factor 2. | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.850 |
LOC102237630 | nop10 | ENSXMAP00000001647 | ENSXMAP00000027030 | TERF1 (TRF1)-interacting nuclear factor 2. | NOP10 ribonucleoprotein homolog (yeast). | 0.840 |
LOC102237630 | rtel1 | ENSXMAP00000001647 | ENSXMAP00000004639 | TERF1 (TRF1)-interacting nuclear factor 2. | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] | 0.765 |
LOC102237630 | tert | ENSXMAP00000001647 | ENSXMAP00000016432 | TERF1 (TRF1)-interacting nuclear factor 2. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.799 |
LOC102237630 | wrap53 | ENSXMAP00000001647 | ENSXMAP00000013617 | TERF1 (TRF1)-interacting nuclear factor 2. | WD repeat containing, antisense to TP53. | 0.771 |
dkc1 | LOC102237630 | ENSXMAP00000023561 | ENSXMAP00000001647 | Dyskeratosis congenita 1, dyskerin. | TERF1 (TRF1)-interacting nuclear factor 2. | 0.838 |
dkc1 | gar1 | ENSXMAP00000023561 | ENSXMAP00000002316 | Dyskeratosis congenita 1, dyskerin. | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. | 0.999 |
dkc1 | nhp2 | ENSXMAP00000023561 | ENSXMAP00000007046 | Dyskeratosis congenita 1, dyskerin. | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.999 |
dkc1 | nop10 | ENSXMAP00000023561 | ENSXMAP00000027030 | Dyskeratosis congenita 1, dyskerin. | NOP10 ribonucleoprotein homolog (yeast). | 0.998 |
dkc1 | rsrc1 | ENSXMAP00000023561 | ENSXMAP00000027610 | Dyskeratosis congenita 1, dyskerin. | Arginine and serine rich coiled-coil 1. | 0.807 |
dkc1 | rtel1 | ENSXMAP00000023561 | ENSXMAP00000004639 | Dyskeratosis congenita 1, dyskerin. | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] | 0.714 |
dkc1 | tert | ENSXMAP00000023561 | ENSXMAP00000016432 | Dyskeratosis congenita 1, dyskerin. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.921 |
dkc1 | trub1 | ENSXMAP00000023561 | ENSXMAP00000014724 | Dyskeratosis congenita 1, dyskerin. | TruB pseudouridine (psi) synthase family member 1. | 0.534 |
dkc1 | trub2 | ENSXMAP00000023561 | ENSXMAP00000015509 | Dyskeratosis congenita 1, dyskerin. | TruB pseudouridine (psi) synthase family member 2. | 0.560 |
dkc1 | wrap53 | ENSXMAP00000023561 | ENSXMAP00000013617 | Dyskeratosis congenita 1, dyskerin. | WD repeat containing, antisense to TP53. | 0.983 |
gar1 | LOC102237630 | ENSXMAP00000002316 | ENSXMAP00000001647 | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. | TERF1 (TRF1)-interacting nuclear factor 2. | 0.662 |
gar1 | dkc1 | ENSXMAP00000002316 | ENSXMAP00000023561 | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. | Dyskeratosis congenita 1, dyskerin. | 0.999 |
gar1 | nhp2 | ENSXMAP00000002316 | ENSXMAP00000007046 | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.999 |