STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSXMAP00000040135CARD domain-containing protein. (92 aa)    
Predicted Functional Partners:
apaf1
Apoptotic peptidase activating factor 1.
    
 0.700
birc6
Baculoviral IAP repeat containing 6.
   
 0.637
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.605
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.605
LOC111610322
Interleukin-1.
   
 0.558
pycard
Uncharacterized protein.
   
 0.536
LOC111608209
PYD and CARD domain containing.
   
 0.536
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.516
cenpn
Centromere protein N.
   
 0.482
ripk4
Receptor-interacting serine-threonine kinase 4.
    
 0.461
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.