| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CED71050.1 | apt | AWOD_I_0957 | AWOD_I_1805 | 5'-nucleotidase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.900 |
| CED71050.1 | gmk | AWOD_I_0957 | AWOD_I_0105 | 5'-nucleotidase. | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.900 |
| CED71050.1 | gpt | AWOD_I_0957 | AWOD_I_0709 | 5'-nucleotidase. | Xanthine phosphoribosyltransferase (xanthine-guanin phosphoribosyltransferase); Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.900 |
| CED71050.1 | guaA | AWOD_I_0957 | AWOD_I_0613 | 5'-nucleotidase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.900 |
| CED71050.1 | guaB | AWOD_I_0957 | AWOD_I_0612 | 5'-nucleotidase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.900 |
| CED71050.1 | guaC | AWOD_I_0957 | AWOD_II_0453 | 5'-nucleotidase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.913 |
| CED71050.1 | purA | AWOD_I_0957 | AWOD_I_0281 | 5'-nucleotidase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.900 |
| CED71050.1 | purA-2 | AWOD_I_0957 | AWOD_I_1059 | 5'-nucleotidase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.900 |
| CED71050.1 | purH | AWOD_I_0957 | AWOD_I_2489 | 5'-nucleotidase. | Bifunctional purine biosynthesis protein PurH. | 0.900 |
| CED71050.1 | surE | AWOD_I_0957 | AWOD_I_2150 | 5'-nucleotidase. | Multifunctional protein SurE (stationary-phase survival protein SurE); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| apt | CED71050.1 | AWOD_I_1805 | AWOD_I_0957 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase. | 0.900 |
| apt | gmk | AWOD_I_1805 | AWOD_I_0105 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.956 |
| apt | gpt | AWOD_I_1805 | AWOD_I_0709 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase (xanthine-guanin phosphoribosyltransferase); Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.941 |
| apt | guaA | AWOD_I_1805 | AWOD_I_0613 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.989 |
| apt | guaC | AWOD_I_1805 | AWOD_II_0453 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.927 |
| apt | purA | AWOD_I_1805 | AWOD_I_0281 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.577 |
| apt | purA-2 | AWOD_I_1805 | AWOD_I_1059 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.570 |
| apt | purH | AWOD_I_1805 | AWOD_I_2489 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Bifunctional purine biosynthesis protein PurH. | 0.958 |
| apt | surE | AWOD_I_1805 | AWOD_I_2150 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Multifunctional protein SurE (stationary-phase survival protein SurE); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.923 |
| gmk | CED71050.1 | AWOD_I_0105 | AWOD_I_0957 | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 5'-nucleotidase. | 0.900 |