| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CED57746.1 | queE | AWOD_II_1130 | AWOD_II_0551 | Putative uncharacterized protein. | Putative organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.701 |
| CED71234.1 | folE | AWOD_I_1149 | AWOD_I_1712 | 6-pyruvoyl tetrahydrobiopterin synthase. | GTP cyclohydrolase I. | 0.982 |
| CED71234.1 | guaA | AWOD_I_1149 | AWOD_I_0613 | 6-pyruvoyl tetrahydrobiopterin synthase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.506 |
| CED71234.1 | queC | AWOD_I_1149 | AWOD_I_1676 | 6-pyruvoyl tetrahydrobiopterin synthase. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.965 |
| CED71234.1 | queE | AWOD_I_1149 | AWOD_II_0551 | 6-pyruvoyl tetrahydrobiopterin synthase. | Putative organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.991 |
| CED71234.1 | queF | AWOD_I_1149 | AWOD_I_0580 | 6-pyruvoyl tetrahydrobiopterin synthase. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.876 |
| folE | CED71234.1 | AWOD_I_1712 | AWOD_I_1149 | GTP cyclohydrolase I. | 6-pyruvoyl tetrahydrobiopterin synthase. | 0.982 |
| folE | nrdD | AWOD_I_1712 | AWOD_II_0295 | GTP cyclohydrolase I. | Anaerobic ribonucleoside-triphosphate reductase. | 0.801 |
| folE | pykA | AWOD_I_1712 | AWOD_II_0550 | GTP cyclohydrolase I. | Pyruvate kinase II; Belongs to the pyruvate kinase family. | 0.809 |
| folE | queC | AWOD_I_1712 | AWOD_I_1676 | GTP cyclohydrolase I. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.470 |
| folE | queE | AWOD_I_1712 | AWOD_II_0551 | GTP cyclohydrolase I. | Putative organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.567 |
| folE | queF | AWOD_I_1712 | AWOD_I_0580 | GTP cyclohydrolase I. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.530 |
| guaA | CED71234.1 | AWOD_I_0613 | AWOD_I_1149 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 6-pyruvoyl tetrahydrobiopterin synthase. | 0.506 |
| guaA | pykA | AWOD_I_0613 | AWOD_II_0550 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Pyruvate kinase II; Belongs to the pyruvate kinase family. | 0.515 |
| guaA | queE | AWOD_I_0613 | AWOD_II_0551 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Putative organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.511 |
| guaA | queF | AWOD_I_0613 | AWOD_I_0580 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.559 |
| nadA | queE | AWOD_I_0947 | AWOD_II_0551 | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | Putative organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.470 |
| nrdD | folE | AWOD_II_0295 | AWOD_I_1712 | Anaerobic ribonucleoside-triphosphate reductase. | GTP cyclohydrolase I. | 0.801 |
| nrdD | pykA | AWOD_II_0295 | AWOD_II_0550 | Anaerobic ribonucleoside-triphosphate reductase. | Pyruvate kinase II; Belongs to the pyruvate kinase family. | 0.900 |
| nrdD | queE | AWOD_II_0295 | AWOD_II_0551 | Anaerobic ribonucleoside-triphosphate reductase. | Putative organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.701 |