| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CED70834.1 | hemX | AWOD_I_0740 | AWOD_I_0066 | Protein SirB, invasion gene expression up-regulator. | Putative uroporphyrin-III C-methyltransferase HemX. | 0.561 |
| CED71696.1 | cysG | AWOD_I_1625 | AWOD_I_0743 | Siroheme synthase, virulence protein VirC. | Siroheme synthase; Belongs to the precorrin methyltransferase family. | 0.994 |
| CED71696.1 | hemC | AWOD_I_1625 | AWOD_I_0068 | Siroheme synthase, virulence protein VirC. | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.707 |
| CED71696.1 | hemD | AWOD_I_1625 | AWOD_I_0067 | Siroheme synthase, virulence protein VirC. | Uroporphyrinogen III synthase HemD; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.452 |
| CED71696.1 | hemX | AWOD_I_1625 | AWOD_I_0066 | Siroheme synthase, virulence protein VirC. | Putative uroporphyrin-III C-methyltransferase HemX. | 0.901 |
| CED71801.1 | hemX | AWOD_I_1735 | AWOD_I_0066 | Putative exported protein. | Putative uroporphyrin-III C-methyltransferase HemX. | 0.571 |
| cya | hemC | AWOD_I_0069 | AWOD_I_0068 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.608 |
| cya | hemD | AWOD_I_0069 | AWOD_I_0067 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Uroporphyrinogen III synthase HemD; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.672 |
| cya | hemX | AWOD_I_0069 | AWOD_I_0066 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Putative uroporphyrin-III C-methyltransferase HemX. | 0.773 |
| cya | hemY | AWOD_I_0069 | AWOD_I_0065 | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | Protein HemY. | 0.775 |
| cysG | CED71696.1 | AWOD_I_0743 | AWOD_I_1625 | Siroheme synthase; Belongs to the precorrin methyltransferase family. | Siroheme synthase, virulence protein VirC. | 0.994 |
| cysG | hemC | AWOD_I_0743 | AWOD_I_0068 | Siroheme synthase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.991 |
| cysG | hemD | AWOD_I_0743 | AWOD_I_0067 | Siroheme synthase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen III synthase HemD; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.930 |
| cysG | hemE | AWOD_I_0743 | AWOD_I_2497 | Siroheme synthase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.928 |
| cysG | hemX | AWOD_I_0743 | AWOD_I_0066 | Siroheme synthase; Belongs to the precorrin methyltransferase family. | Putative uroporphyrin-III C-methyltransferase HemX. | 0.901 |
| hemC | CED71696.1 | AWOD_I_0068 | AWOD_I_1625 | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Siroheme synthase, virulence protein VirC. | 0.707 |
| hemC | cya | AWOD_I_0068 | AWOD_I_0069 | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. | 0.608 |
| hemC | cysG | AWOD_I_0068 | AWOD_I_0743 | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Siroheme synthase; Belongs to the precorrin methyltransferase family. | 0.991 |
| hemC | hemD | AWOD_I_0068 | AWOD_I_0067 | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Uroporphyrinogen III synthase HemD; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.998 |
| hemC | hemE | AWOD_I_0068 | AWOD_I_2497 | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.993 |