| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CED70785.1 | ampD | AWOD_I_0691 | AWOD_I_0414 | MSF transporter. | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | 0.475 |
| CED70785.1 | anmK | AWOD_I_0691 | AWOD_II_0543 | MSF transporter. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.437 |
| CED70785.1 | nagZ | AWOD_I_0691 | AWOD_II_0544 | MSF transporter. | Beta-hexosaminidase (beta-N-acetylhexosaminidase); Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.474 |
| aceE | ampD | AWOD_I_0416 | AWOD_I_0414 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | 0.447 |
| aceE | pdhR | AWOD_I_0416 | AWOD_I_0415 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate dehydrogenase complex repressor. | 0.701 |
| ampD | CED70785.1 | AWOD_I_0414 | AWOD_I_0691 | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | MSF transporter. | 0.475 |
| ampD | aceE | AWOD_I_0414 | AWOD_I_0416 | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.447 |
| ampD | anmK | AWOD_I_0414 | AWOD_II_0543 | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.468 |
| ampD | mpl | AWOD_I_0414 | AWOD_I_2413 | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelat ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.482 |
| ampD | nadC | AWOD_I_0414 | AWOD_I_0413 | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.684 |
| ampD | nagZ | AWOD_I_0414 | AWOD_II_0544 | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | Beta-hexosaminidase (beta-N-acetylhexosaminidase); Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.557 |
| ampD | pdhR | AWOD_I_0414 | AWOD_I_0415 | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | Pyruvate dehydrogenase complex repressor. | 0.509 |
| ampD | pilC | AWOD_I_0414 | AWOD_I_0410 | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | Type IV pilus assembly protein PilC. | 0.427 |
| ampD | pilD | AWOD_I_0414 | AWOD_I_0409 | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | Type IV prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.419 |
| ampD | zapD | AWOD_I_0414 | AWOD_I_0407 | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | UPF0289 protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.512 |
| anmK | CED70785.1 | AWOD_II_0543 | AWOD_I_0691 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | MSF transporter. | 0.437 |
| anmK | ampD | AWOD_II_0543 | AWOD_I_0414 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | 0.468 |
| anmK | nagZ | AWOD_II_0543 | AWOD_II_0544 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Beta-hexosaminidase (beta-N-acetylhexosaminidase); Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.917 |
| mpl | ampD | AWOD_I_2413 | AWOD_I_0414 | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelat ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | AmpD protein (N-acetylmuramoyl-L-alanine amidase). | 0.482 |
| mpl | nagZ | AWOD_I_2413 | AWOD_II_0544 | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelat ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | Beta-hexosaminidase (beta-N-acetylhexosaminidase); Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.581 |