| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CED70659.1 | CED70660.1 | AWOD_I_0565 | AWOD_I_0566 | Putative membrane associated signaling protein. | Small multidrug resistance protein. | 0.405 |
| CED70660.1 | CED70659.1 | AWOD_I_0566 | AWOD_I_0565 | Small multidrug resistance protein. | Putative membrane associated signaling protein. | 0.405 |
| CED70660.1 | flgG | AWOD_I_0566 | AWOD_I_1990 | Small multidrug resistance protein. | Flagellar basal-body rod protein FlgG (distal rod protein); Belongs to the flagella basal body rod proteins family. | 0.437 |
| CED70660.1 | guaA | AWOD_I_0566 | AWOD_I_0613 | Small multidrug resistance protein. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.498 |
| CED70660.1 | macB | AWOD_I_0566 | AWOD_II_1146 | Small multidrug resistance protein. | ABC transporter, permease; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.405 |
| CED70660.1 | topA | AWOD_I_0566 | AWOD_I_1045 | Small multidrug resistance protein. | DNA topoisomerase I (omega protein); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus r [...] | 0.437 |
| flgG | CED70660.1 | AWOD_I_1990 | AWOD_I_0566 | Flagellar basal-body rod protein FlgG (distal rod protein); Belongs to the flagella basal body rod proteins family. | Small multidrug resistance protein. | 0.437 |
| guaA | CED70660.1 | AWOD_I_0613 | AWOD_I_0566 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Small multidrug resistance protein. | 0.498 |
| guaA | macB | AWOD_I_0613 | AWOD_II_1146 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | ABC transporter, permease; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.491 |
| guaA | topA | AWOD_I_0613 | AWOD_I_1045 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | DNA topoisomerase I (omega protein); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus r [...] | 0.564 |
| macB | CED70660.1 | AWOD_II_1146 | AWOD_I_0566 | ABC transporter, permease; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Small multidrug resistance protein. | 0.405 |
| macB | guaA | AWOD_II_1146 | AWOD_I_0613 | ABC transporter, permease; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.491 |
| macB | topA | AWOD_II_1146 | AWOD_I_1045 | ABC transporter, permease; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | DNA topoisomerase I (omega protein); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus r [...] | 0.523 |
| topA | CED70660.1 | AWOD_I_1045 | AWOD_I_0566 | DNA topoisomerase I (omega protein); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus r [...] | Small multidrug resistance protein. | 0.437 |
| topA | guaA | AWOD_I_1045 | AWOD_I_0613 | DNA topoisomerase I (omega protein); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus r [...] | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.564 |
| topA | macB | AWOD_I_1045 | AWOD_II_1146 | DNA topoisomerase I (omega protein); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus r [...] | ABC transporter, permease; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.523 |
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