| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CED56699.1 | apt | AWOD_II_0040 | AWOD_I_1805 | Phosphoribosyl transferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.920 |
| CED56699.1 | gmk | AWOD_II_0040 | AWOD_I_0105 | Phosphoribosyl transferase. | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.926 |
| CED56699.1 | gpt | AWOD_II_0040 | AWOD_I_0709 | Phosphoribosyl transferase. | Xanthine phosphoribosyltransferase (xanthine-guanin phosphoribosyltransferase); Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.917 |
| CED56699.1 | gsk | AWOD_II_0040 | AWOD_II_0452 | Phosphoribosyl transferase. | Inosine-guanosine kinase. | 0.915 |
| CED56699.1 | gsk-2 | AWOD_II_0040 | AWOD_I_0893 | Phosphoribosyl transferase. | Inosine-guanosine kinase. | 0.915 |
| CED56699.1 | guaA | AWOD_II_0040 | AWOD_I_0613 | Phosphoribosyl transferase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.951 |
| CED56699.1 | guaB | AWOD_II_0040 | AWOD_I_0612 | Phosphoribosyl transferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.910 |
| CED56699.1 | guaC | AWOD_II_0040 | AWOD_II_0453 | Phosphoribosyl transferase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.910 |
| CED56699.1 | hpt | AWOD_II_0040 | AWOD_I_0420 | Phosphoribosyl transferase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.924 |
| CED56699.1 | rdgB | AWOD_II_0040 | AWOD_I_2260 | Phosphoribosyl transferase. | Nucleoside-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.904 |
| apt | CED56699.1 | AWOD_I_1805 | AWOD_II_0040 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosyl transferase. | 0.920 |
| apt | gmk | AWOD_I_1805 | AWOD_I_0105 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.956 |
| apt | gpt | AWOD_I_1805 | AWOD_I_0709 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase (xanthine-guanin phosphoribosyltransferase); Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.941 |
| apt | gsk | AWOD_I_1805 | AWOD_II_0452 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-guanosine kinase. | 0.935 |
| apt | gsk-2 | AWOD_I_1805 | AWOD_I_0893 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-guanosine kinase. | 0.935 |
| apt | guaA | AWOD_I_1805 | AWOD_I_0613 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.989 |
| apt | guaC | AWOD_I_1805 | AWOD_II_0453 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.927 |
| apt | hpt | AWOD_I_1805 | AWOD_I_0420 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.920 |
| gmk | CED56699.1 | AWOD_I_0105 | AWOD_II_0040 | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Phosphoribosyl transferase. | 0.926 |
| gmk | apt | AWOD_I_0105 | AWOD_I_1805 | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.956 |