| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CED57019.1 | fruB | AWOD_II_0372 | AWOD_II_1041 | PTS system, IIA component. | PTS system, fructose-specific IIA/FPR component. | 0.737 |
| CED57019.1 | purR | AWOD_II_0372 | AWOD_I_1667 | PTS system, IIA component. | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.523 |
| fruB | CED57019.1 | AWOD_II_1041 | AWOD_II_0372 | PTS system, fructose-specific IIA/FPR component. | PTS system, IIA component. | 0.737 |
| fruB | ptsH | AWOD_II_1041 | AWOD_I_2014 | PTS system, fructose-specific IIA/FPR component. | Phosphocarrier protein Hpr, histidine-containing protein (PTS system). | 0.939 |
| fruB | purR | AWOD_II_1041 | AWOD_I_1667 | PTS system, fructose-specific IIA/FPR component. | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.615 |
| gltB | purR | AWOD_I_2204 | AWOD_I_1667 | Glutamate synthase, large subunit. | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.849 |
| ptsH | fruB | AWOD_I_2014 | AWOD_II_1041 | Phosphocarrier protein Hpr, histidine-containing protein (PTS system). | PTS system, fructose-specific IIA/FPR component. | 0.939 |
| ptsH | purR | AWOD_I_2014 | AWOD_I_1667 | Phosphocarrier protein Hpr, histidine-containing protein (PTS system). | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.525 |
| purR | CED57019.1 | AWOD_I_1667 | AWOD_II_0372 | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | PTS system, IIA component. | 0.523 |
| purR | fruB | AWOD_I_1667 | AWOD_II_1041 | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | PTS system, fructose-specific IIA/FPR component. | 0.615 |
| purR | gltB | AWOD_I_1667 | AWOD_I_2204 | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Glutamate synthase, large subunit. | 0.849 |
| purR | ptsH | AWOD_I_1667 | AWOD_I_2014 | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Phosphocarrier protein Hpr, histidine-containing protein (PTS system). | 0.525 |
| purR | rbsK | AWOD_I_1667 | AWOD_I_1204 | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.533 |
| purR | rpoS | AWOD_I_1667 | AWOD_II_1179 | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.621 |
| purR | rpoS-2 | AWOD_I_1667 | AWOD_I_2147 | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | RNA polymerase sigma subunit RpoS (sigma-38); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.621 |
| purR | tfoX | AWOD_I_1667 | AWOD_I_1668 | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Putative DNA transformation protein TfoX. | 0.571 |
| purR | torD | AWOD_I_1667 | AWOD_I_1666 | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Chaperone protein TorD; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily. | 0.581 |
| purR | torR | AWOD_I_1667 | AWOD_I_1665 | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | torCAD operon transcriptional regulatory protein TorR. | 0.554 |
| rbsK | purR | AWOD_I_1204 | AWOD_I_1667 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.533 |
| rpoS | purR | AWOD_II_1179 | AWOD_I_1667 | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | HTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.621 |
