| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CED57209.1 | btuR | AWOD_II_0569 | AWOD_I_1874 | Putative cobalamin synthesis protein. | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.433 |
| CED57209.1 | cobQ | AWOD_II_0569 | AWOD_II_0305 | Putative cobalamin synthesis protein. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.404 |
| CED57209.1 | hisI | AWOD_II_0569 | AWOD_I_1011 | Putative cobalamin synthesis protein. | Histidine biosynthesis bifunctional protein HisIE [includes: phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. | 0.634 |
| CED70560.1 | btuR | AWOD_I_0466 | AWOD_I_1874 | Cobalamin biosynthesis protein. | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.974 |
| CED70560.1 | cobQ | AWOD_I_0466 | AWOD_II_0305 | Cobalamin biosynthesis protein. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.983 |
| CED70560.1 | cysG | AWOD_I_0466 | AWOD_I_0743 | Cobalamin biosynthesis protein. | Siroheme synthase; Belongs to the precorrin methyltransferase family. | 0.424 |
| CED71938.1 | btuR | AWOD_I_1873 | AWOD_I_1874 | Putative metal dependent phosphohydrolase. | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.563 |
| btuR | CED57209.1 | AWOD_I_1874 | AWOD_II_0569 | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Putative cobalamin synthesis protein. | 0.433 |
| btuR | CED70560.1 | AWOD_I_1874 | AWOD_I_0466 | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobalamin biosynthesis protein. | 0.974 |
| btuR | CED71938.1 | AWOD_I_1874 | AWOD_I_1873 | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Putative metal dependent phosphohydrolase. | 0.563 |
| btuR | cobQ | AWOD_I_1874 | AWOD_II_0305 | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.986 |
| btuR | cysG | AWOD_I_1874 | AWOD_I_0743 | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Siroheme synthase; Belongs to the precorrin methyltransferase family. | 0.567 |
| btuR | hisI | AWOD_I_1874 | AWOD_I_1011 | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Histidine biosynthesis bifunctional protein HisIE [includes: phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. | 0.559 |
| btuR | metH | AWOD_I_1874 | AWOD_I_2336 | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.633 |
| cobQ | CED57209.1 | AWOD_II_0305 | AWOD_II_0569 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Putative cobalamin synthesis protein. | 0.404 |
| cobQ | CED70560.1 | AWOD_II_0305 | AWOD_I_0466 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Cobalamin biosynthesis protein. | 0.983 |
| cobQ | btuR | AWOD_II_0305 | AWOD_I_1874 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.986 |
| cobQ | cysG | AWOD_II_0305 | AWOD_I_0743 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Siroheme synthase; Belongs to the precorrin methyltransferase family. | 0.562 |
| cobQ | metH | AWOD_II_0305 | AWOD_I_2336 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.584 |
| cysG | CED70560.1 | AWOD_I_0743 | AWOD_I_0466 | Siroheme synthase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein. | 0.424 |