STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
CED72236.1sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] (205 aa)    
Predicted Functional Partners:
CED72235.1
sigma-E factor regulatory protein RseB precursor.
 
 
 0.997
rpoE
RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.975
CED57540.1
RNA polymerase, sigma 70 factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.914
CED70469.1
Exported serine protease.
  
 
 0.905
CED57481.1
RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.897
CED72234.1
sigma-E factor regulatory protein RseC.
  
  
 0.879
sspB
Stringent starvation protein B.
    
 
 0.784
nlpI
Lipoprotein NlpI; CDS is truncated at the C-terminus in comparison to orthologues.
  
   
 0.772
rraB
Putative uncharacterized protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.765
yihI
Putative uncharacterized protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.759
Your Current Organism:
Aliivibrio wodanis
NCBI taxonomy Id: 80852
Other names: A. wodanis, ATCC BAA-104, Aliivibrio wodanis (Lunder et al. 2000) Urbanczyk et al. 2007, DSM 22225, LMG 24053, LMG:24053, NCIMB 13582, Vibrio wodanis, Vibrio wodanis Lunder et al. 2000, strain NVI 88/441
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