| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MVIS_0056 | rseB | MVIS_0056 | MVIS_0422 | Putative uncharacterized protein. | sigma-E factor regulatory protein RseB precursor. | 0.612 |
| MVIS_0662 | ftsQ | MVIS_0662 | MVIS_4182 | Putative uncharacterized SAM-dependent methyltransferase. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.590 |
| MVIS_0662 | rseB | MVIS_0662 | MVIS_0422 | Putative uncharacterized SAM-dependent methyltransferase. | sigma-E factor regulatory protein RseB precursor. | 0.736 |
| MVIS_0662 | rseC | MVIS_0662 | MVIS_0423 | Putative uncharacterized SAM-dependent methyltransferase. | sigma-E factor regulatory protein RseC. | 0.433 |
| ecfE | ftsQ | MVIS_3844 | MVIS_4182 | Protease EcfE. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.528 |
| ecfE | lepB | MVIS_3844 | MVIS_0425 | Protease EcfE. | Signal peptidase I (leader peptidase I); Belongs to the peptidase S26 family. | 0.638 |
| ecfE | rseA | MVIS_3844 | MVIS_0421 | Protease EcfE. | sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.562 |
| ecfE | rseB | MVIS_3844 | MVIS_0422 | Protease EcfE. | sigma-E factor regulatory protein RseB precursor. | 0.600 |
| ecfE | rseC | MVIS_3844 | MVIS_0423 | Protease EcfE. | sigma-E factor regulatory protein RseC. | 0.493 |
| ftsQ | MVIS_0662 | MVIS_4182 | MVIS_0662 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Putative uncharacterized SAM-dependent methyltransferase. | 0.590 |
| ftsQ | ecfE | MVIS_4182 | MVIS_3844 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Protease EcfE. | 0.528 |
| ftsQ | recO | MVIS_4182 | MVIS_0428 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | DNA repair protein RecO (recombination protein O); Involved in DNA repair and RecF pathway recombination. | 0.487 |
| ftsQ | rseB | MVIS_4182 | MVIS_0422 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | sigma-E factor regulatory protein RseB precursor. | 0.597 |
| gcvR | rseB | MVIS_3530 | MVIS_0422 | Glycine cleavage system transcriptional repressor. | sigma-E factor regulatory protein RseB precursor. | 0.607 |
| lepB | ecfE | MVIS_0425 | MVIS_3844 | Signal peptidase I (leader peptidase I); Belongs to the peptidase S26 family. | Protease EcfE. | 0.638 |
| lepB | recO | MVIS_0425 | MVIS_0428 | Signal peptidase I (leader peptidase I); Belongs to the peptidase S26 family. | DNA repair protein RecO (recombination protein O); Involved in DNA repair and RecF pathway recombination. | 0.815 |
| lepB | rpoE | MVIS_0425 | MVIS_0420 | Signal peptidase I (leader peptidase I); Belongs to the peptidase S26 family. | RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily. | 0.493 |
| lepB | rseA | MVIS_0425 | MVIS_0421 | Signal peptidase I (leader peptidase I); Belongs to the peptidase S26 family. | sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.520 |
| lepB | rseB | MVIS_0425 | MVIS_0422 | Signal peptidase I (leader peptidase I); Belongs to the peptidase S26 family. | sigma-E factor regulatory protein RseB precursor. | 0.606 |
| lepB | rseC | MVIS_0425 | MVIS_0423 | Signal peptidase I (leader peptidase I); Belongs to the peptidase S26 family. | sigma-E factor regulatory protein RseC. | 0.640 |