node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MVIS_3491 | ispA | MVIS_3491 | MVIS_3732 | Putative lipoprotein. | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.828 |
MVIS_3491 | ispB | MVIS_3491 | MVIS_0508 | Putative lipoprotein. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.828 |
hemC | ispA | MVIS_0044 | MVIS_3732 | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.575 |
hemC | ispB | MVIS_0044 | MVIS_0508 | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.571 |
hemC | xseB | MVIS_0044 | MVIS_3731 | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.713 |
ispA | MVIS_3491 | MVIS_3732 | MVIS_3491 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Putative lipoprotein. | 0.828 |
ispA | hemC | MVIS_3732 | MVIS_0044 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.575 |
ispA | ispB | MVIS_3732 | MVIS_0508 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.926 |
ispA | ndk | MVIS_3732 | MVIS_0665 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.696 |
ispA | rpsE | MVIS_3732 | MVIS_4285 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.547 |
ispA | uppS | MVIS_3732 | MVIS_3847 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.971 |
ispA | xseA | MVIS_3732 | MVIS_0737 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.610 |
ispA | xseB | MVIS_3732 | MVIS_3731 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.924 |
ispB | MVIS_3491 | MVIS_0508 | MVIS_3491 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Putative lipoprotein. | 0.828 |
ispB | hemC | MVIS_0508 | MVIS_0044 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.571 |
ispB | ispA | MVIS_0508 | MVIS_3732 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.926 |
ispB | menA | MVIS_0508 | MVIS_1331 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.859 |
ispB | ndk | MVIS_0508 | MVIS_0665 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.671 |
ispB | rpsE | MVIS_0508 | MVIS_4285 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.608 |
ispB | ubiA | MVIS_0508 | MVIS_0157 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.921 |