Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hmgA-23-hydroxy-3-methylglutaryl-CoA reductase. (910 aa)    
Predicted Functional Partners:
MVIS_1671
Pyruvate phosphate dikinase.
 
     0.909
MVIS_1673
Putative AMP-dependent synthetase and ligase.
 
     0.819
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
   
 
 0.798
MVIS_1672
Putative uncharacterized protein.
  
    0.787
MVIS_1674
Putative membrane associated phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.764
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
   
  
 0.685
cnf1
Cytotoxic necritizing factor.
    
 
 0.659
MVIS_0849
FAD dependent oxidoreductase.
 
  
 0.632
rho
Transcription termination factor rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
      
 0.618
ispB
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 0.609
Your Current Organism:
Moritella viscosa
NCBI taxonomy Id: 80854
Other names: ATCC BAA-105, M. viscosa, Moritella viscosa (Lunder et al. 2000) Benediktsdottir et al. 2000, NCIMB 13584, Vibrio viscosus, Vibrio viscosus Lunder et al. 2000, strain NVI 88/478
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