Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MVIS_1683Putative AcnD-accessory protein PrpF. (403 aa)    
Predicted Functional Partners:
MVIS_1682
Aconitate hydratase.
 
 
 0.999
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.936
acnB
Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.
    
 0.916
MVIS_1681
Citrate synthase; Belongs to the citrate synthase family.
 
  
 0.881
MVIS_1679
HTH-type transcriptional regulator, GntR family.
 
  
 0.799
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
 
 
   0.690
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
  
 0.640
MVIS_1684
Putative exported protein.
       0.496
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
   
    0.406
MVIS_1524
DNA topoisomerase I.
   
    0.406
Your Current Organism:
Moritella viscosa
NCBI taxonomy Id: 80854
Other names: ATCC BAA-105, M. viscosa, Moritella viscosa (Lunder et al. 2000) Benediktsdottir et al. 2000, NCIMB 13584, Vibrio viscosus, Vibrio viscosus Lunder et al. 2000, strain NVI 88/478
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