node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIS37707.1 | SIS37722.1 | SAMN05421779_101291 | SAMN05421779_101293 | BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | Ribonuclease J. | 0.785 |
SIS37707.1 | SIS37729.1 | SAMN05421779_101291 | SAMN05421779_101294 | BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | methylmalonyl-CoA epimerase. | 0.641 |
SIS37707.1 | SIS59618.1 | SAMN05421779_101291 | SAMN05421779_102719 | BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.614 |
SIS37707.1 | coaD | SAMN05421779_101291 | SAMN05421779_105356 | BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.572 |
SIS37707.1 | coaX | SAMN05421779_101291 | SAMN05421779_101292 | BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.850 |
SIS37707.1 | panC | SAMN05421779_101291 | SAMN05421779_102727 | BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.674 |
SIS37722.1 | SIS37707.1 | SAMN05421779_101293 | SAMN05421779_101291 | Ribonuclease J. | BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | 0.785 |
SIS37722.1 | SIS37729.1 | SAMN05421779_101293 | SAMN05421779_101294 | Ribonuclease J. | methylmalonyl-CoA epimerase. | 0.696 |
SIS37722.1 | coaX | SAMN05421779_101293 | SAMN05421779_101292 | Ribonuclease J. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.845 |
SIS37729.1 | SIS37707.1 | SAMN05421779_101294 | SAMN05421779_101291 | methylmalonyl-CoA epimerase. | BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | 0.641 |
SIS37729.1 | SIS37722.1 | SAMN05421779_101294 | SAMN05421779_101293 | methylmalonyl-CoA epimerase. | Ribonuclease J. | 0.696 |
SIS37729.1 | coaX | SAMN05421779_101294 | SAMN05421779_101292 | methylmalonyl-CoA epimerase. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.696 |
SIS59618.1 | SIS37707.1 | SAMN05421779_102719 | SAMN05421779_101291 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | 0.614 |
SIS59618.1 | SIT07699.1 | SAMN05421779_102719 | SAMN05421779_106193 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | WD40 repeat. | 0.670 |
SIS59618.1 | coaD | SAMN05421779_102719 | SAMN05421779_105356 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.893 |
SIS59618.1 | coaX | SAMN05421779_102719 | SAMN05421779_101292 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.882 |
SIS59618.1 | panC | SAMN05421779_102719 | SAMN05421779_102727 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.907 |
SIS59618.1 | tmk | SAMN05421779_102719 | SAMN05421779_101695 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.581 |
SIT01418.1 | coaX | SAMN05421779_105345 | SAMN05421779_101292 | Tetrapyrrole methylase family protein / MazG family protein/ATP diphosphatase. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.809 |
SIT04993.1 | coaX | SAMN05421779_10625 | SAMN05421779_101292 | Molecular chaperone Hsp33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.644 |