STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS38863.1DNA-binding transcriptional regulator, MerR family. (149 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.920
SIS51140.1
Glutamate synthase (NADPH) large subunit.
    
 0.859
SIS36618.1
SH3 domain-containing protein.
  
 
 0.809
SIS46359.1
DnaJ-class molecular chaperone with C-terminal Zn finger domain.
  
 
 0.795
SIS46641.1
DnaJ domain-containing protein.
  
 
 0.795
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.795
SIS59942.1
DnaJ-class molecular chaperone with C-terminal Zn finger domain.
  
 
 0.795
dnaX
DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
  0.783
SIS39002.1
Response regulator receiver domain-containing protein.
   
 0.778
SIT11949.1
Hypothetical protein.
   
 0.778
Your Current Organism:
Insolitispirillum peregrinum
NCBI taxonomy Id: 80876
Other names: ATCC 15387, Aquaspirillum peregrinum, CCUG 13795, I. peregrinum, IFO 14922, JCM 21450, LMG 4340, LMG:4340, NBRC 14922, Spirillum peregrinum
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