STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS54170.18-oxo-dGTP diphosphatase. (341 aa)    
Predicted Functional Partners:
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.903
SIS75308.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.877
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.842
SIS46597.1
Mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.820
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
  
 0.792
SIT07577.1
Lysine N6-hydroxylase.
  
 
 0.792
SIT20774.1
Yersiniabactin nonribosomal peptide/polyketide synthase.
  
 
 0.786
SIT00488.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.754
SIS76032.1
Hypothetical protein.
   
  0.753
SIS51140.1
Glutamate synthase (NADPH) large subunit.
  
 
 0.749
Your Current Organism:
Insolitispirillum peregrinum
NCBI taxonomy Id: 80876
Other names: ATCC 15387, Aquaspirillum peregrinum, CCUG 13795, I. peregrinum, IFO 14922, JCM 21450, LMG 4340, LMG:4340, NBRC 14922, Spirillum peregrinum
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