STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS69065.1Pentapeptide repeat-containing protein. (192 aa)    
Predicted Functional Partners:
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
 
 0.847
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.847
SIS69046.1
Methanol/ethanol dehydrogenase mdh2 apoprotein.
 
  
 0.799
SIS41849.1
Outer membrane protein OmpA.
  
 
 0.772
SIS38430.1
Predicted ATPase.
 
 
 0.765
SIS42245.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.748
SIS38399.1
Flp pilus assembly protein TadD, contains TPR repeats.
  
  
 0.733
SIT08450.1
AAA ATPase domain-containing protein.
 
  
 0.697
SIS87125.1
Cytochrome c-550 PedF.
 
    0.683
SIS37007.1
Flp pilus assembly protein TadD, contains TPR repeats.
  
  
 0.680
Your Current Organism:
Insolitispirillum peregrinum
NCBI taxonomy Id: 80876
Other names: ATCC 15387, Aquaspirillum peregrinum, CCUG 13795, I. peregrinum, IFO 14922, JCM 21450, LMG 4340, LMG:4340, NBRC 14922, Spirillum peregrinum
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