STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS95867.12-keto-4-pentenoate hydratase. (266 aa)    
Predicted Functional Partners:
SIS95902.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.986
SIS95884.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
 0.983
SIS52173.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.943
SIS95847.1
2-hydroxy-6-oxonona-2,4-dienedioate hydrolase.
 
 
 0.939
SIS96294.1
2,4-dihydroxyhept-2-enedioate aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 0.930
SIS52143.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
 0.926
SIS96330.1
5-carboxymethyl-2-hydroxymuconate delta isomerase.
 
 
 0.907
SIS96346.1
3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
  
 0.847
SIT19219.1
5-carboxymethyl-2-hydroxymuconate isomerase.
  
 
 0.775
SIS52280.1
2-hydroxy-6-ketonona-2,4-dienedioate hydrolase.
 
 
 0.744
Your Current Organism:
Insolitispirillum peregrinum
NCBI taxonomy Id: 80876
Other names: ATCC 15387, Aquaspirillum peregrinum, CCUG 13795, I. peregrinum, IFO 14922, JCM 21450, LMG 4340, LMG:4340, NBRC 14922, Spirillum peregrinum
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