Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101170075Zgc:113142; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)    
Predicted Functional Partners:
oxct1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
     
 0.700
clpx
Caseinolytic mitochondrial matrix peptidase chaperone subunit b.
     
 0.480
dhtkd1
Dehydrogenase E1 and transketolase domain containing 1.
   
 
 0.478
Acadm
Acyl-CoA_dh_1 domain-containing protein.
   
 
 0.470
eci1
Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.461
hmgcll1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.
     
 0.460
hmgcl
3-hydroxy-3-methylglutaryl-CoA lyase.
     
 0.460
clpp
ATP-dependent Clp protease proteolytic subunit.
     
 0.454
Mdh2
Malate dehydrogenase.
   
 
 0.447
hadh
Hydroxyacyl-CoA dehydrogenase.
   
 
 0.440
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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