Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
upf3bUPF3B regulator of nonsense mediated mRNA decay. (457 aa)    
Predicted Functional Partners:
UPF1
UPF1 RNA helicase and ATPase.
    
 0.998
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
   
 0.998
smg5
SMG5 nonsense mediated mRNA decay factor.
   
 0.993
smg6
SMG6 nonsense mediated mRNA decay factor.
   
 0.984
smg7
SMG7 nonsense mediated mRNA decay factor.
   
 0.971
eif4a3
Eukaryotic translation initiation factor 4A3.
   
 0.967
rnps1
RNA binding protein S1, serine-rich domain.
    
 0.962
rbm8a
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
   
 0.958
casc3
Casc3 exon junction complex subunit.
    
 0.957
LOC101167611
Mago homolog, exon junction complex subunit.
    
 0.953
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.