Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101161809RAB40c, member RAS oncogene family. (279 aa)    
Predicted Functional Partners:
rabggtb
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
   
 0.808
eloc
Elongin C paralog b; Belongs to the SKP1 family.
   
 
 0.789
ELOB
Ubiquitin-like domain-containing protein.
    
 
 0.789
CUL5
Cullin 5; Belongs to the cullin family.
    
 
 0.713
LOC101154889
Cullin 5; Belongs to the cullin family.
    
 
 0.713
LOC101158129
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.659
H2LNT6_ORYLA
Rab interacting lysosomal protein-like 2.
    
 
 0.651
psme3ip1
Family with sequence similarity 192 member A.
    
   0.625
mthfsd
Methenyltetrahydrofolate synthetase domain containing.
   
    0.625
isca1
Iron-sulfur cluster assembly 1.
    
   0.624
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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