Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hdac7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (940 aa)    
Predicted Functional Partners:
sirt1
Deacetylase sirtuin-type domain-containing protein.
    
 0.763
LOC101170553
NME/NM23 family member 8; Belongs to the NDK family.
  
 
 0.750
H2M348_ORYLA
Tudor-knot domain-containing protein.
    
 0.717
arid4b
Translocase of outer mitochondrial membrane 20.
    
 0.717
Arid4a
Tudor domain-containing protein.
    
 0.717
vcp
Valosin containing protein; Belongs to the AAA ATPase family.
  
 0.672
LOC101160447
RAN binding protein 2.
   
 0.671
Wdr90
WD_REPEATS_REGION domain-containing protein.
   
 0.650
ENSORLP00000042816
Uncharacterized protein.
   
 0.650
LOC101168870
E1A binding protein p300 b.
    
 0.639
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (14%) [HD]