Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LGALS4Galectin. (323 aa)    
Predicted Functional Partners:
phgdh
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
      
 0.693
galk1
Galactokinase 1.
      
 0.606
galm
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
      
 0.604
paics
AIRC domain-containing protein.
      
 0.600
LOC101157460
4-hydroxyphenylpyruvate dioxygenase.
      
 0.586
LOC101165831
4-hydroxyphenylpyruvate dioxygenase.
      
 0.586
ENSORLP00000043209
Alpha-1-microglobulin/bikunin precursor.
      
 0.549
tmem97
Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
    
 0.547
LOC101172654
Uncharacterized protein.
   
  
 0.546
LOC101161235
Troponin I4b, tandem duplicate 2.
   
  
 0.546
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.