Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
crybb1Crystallin, beta B1; Belongs to the beta/gamma-crystallin family. (231 aa)    
Predicted Functional Partners:
cryaa
Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens; Belongs to the small heat shock protein (HSP20) family.
   
  
 0.807
BFSP1
Beaded filament structural protein 1; Belongs to the intermediate filament family.
      
 0.700
LOC101157015
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.589
bfsp2
Beaded filament structural protein 2, phakinin; Belongs to the intermediate filament family.
   
 0.573
lgsn
Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family.
   
  
 0.536
srrd
SRR1 domain containing.
      
 0.535
prr18
Proline rich 18.
   
 
 0.531
LOC101166980
Homeobox protein.
      
 0.518
ENSORLP00000032656
Uncharacterized protein.
    
 0.518
H2M6E4_ORYLA
Uncharacterized protein.
    
 0.516
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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