STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cul4bCullin 4B; Belongs to the cullin family. (845 aa)    
Predicted Functional Partners:
ddb1
Damage-specific DNA binding protein 1.
   
 0.978
H2MG95_ORYLA
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.966
DCAF1
DDB1 and CUL4 associated factor 1.
   
 0.960
dda1
DET1 and DDB1 associated 1.
    
 0.958
dcaf11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.957
dtl
Denticleless E3 ubiquitin protein ligase homolog (Drosophila).
    
 0.949
ddb2
Damage-specific DNA binding protein 2.
    
 0.937
rnf7
Ring finger protein 7.
    
 0.919
cops5
COP9 signalosome subunit 5.
    
 0.918
LOC101154851
Cullin 4A; Belongs to the cullin family.
  
  
0.917
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.