STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpm5Transient receptor potential cation channel, subfamily M, member 5. (1146 aa)    
Predicted Functional Partners:
nudt9
Nudix (nucleoside diphosphate linked moiety X)-type motif 9.
 
   
 0.811
trpa1
Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family.
     
 0.707
plcb2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 
 0.619
LOC101164189
Potassium inwardly-rectifying channel, subfamily J, member 16.
    
 
 0.615
pkd2l1
EF-hand domain-containing protein.
   
  
 0.609
LOC101155104
Inositol 1,4,5-trisphosphate receptor, type 1b.
   
 
 0.601
KCNJ15
Potassium voltage-gated channel subfamily J member 15.
    
 
 0.599
LOC101158057
Canopy FGF signaling regulator 3.
      
 0.599
itpr3
Inositol 1,4,5-trisphosphate receptor, type 3.
   
 
 0.544
trpv4
Transient receptor potential cation channel, subfamily V, member 4; Belongs to the transient receptor (TC 1.A.4) family.
   
 
 0.536
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.