Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101163430Interferon regulatory factor. (293 aa)    
Predicted Functional Partners:
mdm2
MDM2 proto-oncogene.
    
 0.989
stub1
STIP1 homology and U-Box containing protein 1.
    
 
 0.969
LOC101154761
Signal transducer and activator of transcription.
   
 0.948
irf2
Interferon regulatory factor.
   
 0.908
LOC101160197
E1A binding protein p300 a.
    
 0.896
LOC101168870
E1A binding protein p300 b.
    
 0.896
LOC101173855
Signal transducer and activator of transcription.
   
 0.892
stat3
Signal transducer and activator of transcription.
   
 0.853
LOC101161521
Signal transducer and activator of transcription.
   
 0.808
il10
Interleukin 10.
   
 
 0.750
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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