STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
akip1A kinase (PRKA) interacting protein 1. (170 aa)    
Predicted Functional Partners:
LOC101160164
Dehydrogenase/reductase (SDR family) member 7Ca.
      
 0.674
dhrs7c
Dehydrogenase/reductase (SDR family) member 7Cb.
      
 0.674
LSM10
LSM10, U7 small nuclear RNA associated.
      
 0.603
prkx
Protein kinase X-linked; Belongs to the protein kinase superfamily.
    
 
 0.521
poc1b
POC1 centriolar protein B.
    
   0.504
POC1A
WD_REPEATS_REGION domain-containing protein.
    
   0.504
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.498
gpkow
G patch domain and KOW motifs.
      
 0.483
ube2n
Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family.
      
 0.480
LOC101170318
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
      
 0.480
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.